SLTM Antibody (PACO20547)
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주문- SKU:
- PACO20547
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLTM Antibody (PACO20547) |
Antibody SKU: | PACO20547 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human SLTM |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20547(SLTM Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | SLTM (SAFB-like, transcription modulator), also known as MET (modulator of estrogen-induced transcription), is a 1,034 amino acid, protein that localizes to punctate structures within the nucleus and contains one SAP domain and one RNA recognition motif. When expressed at high levels, SLTM functions to inhibit transcription and may, ultimately, lead to apoptosis. Multiple isoforms of SLTM exist due to alternative splicing events. The gene encoding SLTM maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. |
Synonyms: | SAFB-like, transcription modulator |
UniProt Protein Function: | SLTM: When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis. |
UniProt Protein Details: | Protein type:RNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 15q22.1 Cellular Component: nucleoplasm Molecular Function:nucleotide binding Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis |
UniProt Code: | Q9NWH9 |
NCBI GenInfo Identifier: | 114325436 |
NCBI Gene ID: | 79811 |
NCBI Accession: | AAH46119.3 |
UniProt Secondary Accession: | Q9NWH9,Q2VPK7, Q52MB3, Q658J7, Q6ZNF2, Q86TK6, Q9H7C3 Q9H8U9, A8K5V8, B2RTX3, |
UniProt Related Accession: | Q9NWH9 |
Molecular Weight: | 71,067 Da |
NCBI Full Name: | SLTM protein, partial |
NCBI Synonym Full Names: | SAFB-like, transcription modulator |
NCBI Official Symbol: | SLTM |
NCBI Official Synonym Symbols: | Met |
NCBI Protein Information: | SAFB-like transcription modulator; modulator of estrogen-induced transcription |
UniProt Protein Name: | SAFB-like transcription modulator |
UniProt Synonym Protein Names: | Modulator of estrogen-induced transcription |
Protein Family: | SAFB-like transcription modulator |
UniProt Gene Name: | SLTM |
UniProt Entry Name: | SLTM_HUMAN |