SLC9A3 Antibody (PACO17919)
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주문- SKU:
- PACO17919
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC9A3 Antibody (PACO17919) |
Antibody SKU: | PACO17919 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human SLC9A3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17919(SLC9A3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17919(SLC9A3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Involved in pH regulation to eliminate acid, generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels |
Synonyms: | Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
UniProt Protein Function: | NHE3: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Binds SLC9A3R1 and SLC9A3R2. Interacts with SHANK2. Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. |
UniProt Protein Details: | Protein type:Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 5p15.3 Cellular Component: cell surface; brush border membrane; apical plasma membrane; integral to membrane; plasma membrane; brush border Molecular Function:protein binding; sodium:hydrogen antiporter activity; PDZ domain binding Biological Process: regulation of pH; ion transport; transmembrane transport |
UniProt Code: | P48764 |
NCBI GenInfo Identifier: | 194239733 |
NCBI Gene ID: | 6550 |
NCBI Accession: | NP_004165.2 |
UniProt Secondary Accession: | P48764,Q3MIW3, B7ZKR2, E9PF67, |
UniProt Related Accession: | P48764 |
Molecular Weight: | 91,904 Da |
NCBI Full Name: | sodium/hydrogen exchanger 3 isoform 1 |
NCBI Synonym Full Names: | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
NCBI Official Symbol: | SLC9A3 |
NCBI Official Synonym Symbols: | NHE3 |
NCBI Protein Information: | sodium/hydrogen exchanger 3 |
UniProt Protein Name: | Sodium/hydrogen exchanger 3 |
UniProt Synonym Protein Names: | Na(+)/H(+) exchanger 3 |
UniProt Gene Name: | SLC9A3 |
UniProt Entry Name: | SL9A3_HUMAN |
Antibodies |
Anti-SLC9A3 Antibody (CAB17532) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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