SLC39A6 Antibody (PACO43985)
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주문- SKU:
- PACO43985
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC39A6 Antibody (PACO43985) |
Antibody SKU: | PACO43985 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Zinc transporter ZIP6 protein (170-320AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: SLC39A6 antibody at 10µg/ml. Lane 1: Hela whole cell lysate. Lane 2: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 86, 49 kDa. Observed band size: 86 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43985 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43985 at dilution of 1:100. |
Background: | May act as a zinc-influx transporter. |
Synonyms: | Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6), SLC39A6, LIV1 ZIP6 |
UniProt Protein Function: | SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter Chromosomal Location of Human Ortholog: 18q12.2 Cellular Component: cell surface; integral to plasma membrane; endoplasmic reticulum; plasma membrane Molecular Function:zinc ion transmembrane transporter activity Biological Process: cellular zinc ion homeostasis; transmembrane transport |
NCBI Summary: | Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q13433 |
NCBI GenInfo Identifier: | 292495066 |
NCBI Gene ID: | 25800 |
NCBI Accession: | Q13433.3 |
UniProt Related Accession: | Q13433 |
Molecular Weight: | |
NCBI Full Name: | Zinc transporter ZIP6 |
NCBI Synonym Full Names: | solute carrier family 39 member 6 |
NCBI Official Symbol: | SLC39A6 |
NCBI Official Synonym Symbols: | ZIP6; LIV-1 |
NCBI Protein Information: | zinc transporter ZIP6 |
UniProt Protein Name: | Zinc transporter ZIP6 |
UniProt Synonym Protein Names: | Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6 |
UniProt Gene Name: | SLC39A6 |
UniProt Entry Name: | S39A6_HUMAN |