SLC1A2 Antibody (PACO17807)
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주문- SKU:
- PACO17807
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC1A2 Antibody (PACO17807) |
Antibody SKU: | PACO17807 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human SLC1A2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17807(SLC1A2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17807(SLC1A2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. |
Synonyms: | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
UniProt Protein Function: | Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. |
NCBI Summary: | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] |
UniProt Code: | P43004 |
NCBI GenInfo Identifier: | 3041668 |
NCBI Gene ID: | 6506 |
NCBI Accession: | P43004.2 |
UniProt Secondary Accession: | P43004,Q14417, Q541G6, B4DQE9, U3KQQ4, |
UniProt Related Accession: | P43004 |
Molecular Weight: | 61,008 Da |
NCBI Full Name: | Excitatory amino acid transporter 2 |
NCBI Synonym Full Names: | solute carrier family 1 member 2 |
NCBI Official Symbol: | SLC1A2 |
NCBI Official Synonym Symbols: | HBGT; EAAT2; GLT-1 |
NCBI Protein Information: | excitatory amino acid transporter 2 |
UniProt Protein Name: | Excitatory amino acid transporter 2 |
UniProt Synonym Protein Names: | Glutamate/aspartate transporter II; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2 |
Protein Family: | Excitatory amino acid transporter |
UniProt Gene Name: | SLC1A2 |
UniProt Entry Name: | EAA2_HUMAN |