SHOX2 Antibody (PACO44595)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO44595
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | SHOX2 Antibody (PACO44595) |
Antibody SKU: | PACO44595 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Short stature homeobox protein 2 protein (72-331AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human heart tissue using PACO44595 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human lung tissue using PACO44595 at dilution of 1:100. |
Background: | May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. |
Synonyms: | Short stature homeobox protein 2 (Homeobox protein Og12X) (Paired-related homeobox protein SHOT), SHOX2, OG12X SHOT |
UniProt Protein Function: | SHOX2: May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. Belongs to the paired homeobox family. Bicoid subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 3q25.32 Cellular Component: nucleoplasm; nuclear membrane; mitochondrion Molecular Function:sequence-specific DNA binding Biological Process: embryonic forelimb morphogenesis; nervous system development; heart development; negative regulation of transcription from RNA polymerase II promoter; chondrocyte development; osteoblast differentiation; positive regulation of skeletal muscle fiber development; embryonic digestive tract morphogenesis; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; positive regulation of axonogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of chondrocyte differentiation; skeletal development |
NCBI Summary: | This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] |
UniProt Code: | O60902 |
NCBI GenInfo Identifier: | 89145413 |
NCBI Gene ID: | 6474 |
NCBI Accession: | NP_006875 |
UniProt Related Accession: | O60902 |
Molecular Weight: | 35kDa |
NCBI Full Name: | short stature homeobox protein 2 isoform a |
NCBI Synonym Full Names: | short stature homeobox 2 |
NCBI Official Symbol: | SHOX2 |
NCBI Official Synonym Symbols: | OG12; SHOT; OG12X |
NCBI Protein Information: | short stature homeobox protein 2 |
UniProt Protein Name: | Short stature homeobox protein 2 |
UniProt Synonym Protein Names: | Homeobox protein Og12X; Paired-related homeobox protein SHOT |
Protein Family: | Short stature homeobox protein |
UniProt Gene Name: | SHOX2 |
UniProt Entry Name: | SHOX2_HUMAN |
Antibodies |
Anti-SHOX2 Antibody (CAB8309) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |