SERPINB2 Antibody (PACO16832)
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주문- SKU:
- PACO16832
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SERPINB2 Antibody (PACO16832) |
Antibody SKU: | PACO16832 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human SERPINB2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16832(SERPINB2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy. |
Synonyms: | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
UniProt Protein Function: | SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: fibrinolysis; blood coagulation; negative regulation of apoptosis |
UniProt Code: | P05120 |
NCBI GenInfo Identifier: | 1352712 |
NCBI Gene ID: | 5055 |
NCBI Accession: | P05120.2 |
UniProt Secondary Accession: | P05120,Q96E96, |
UniProt Related Accession: | P05120 |
Molecular Weight: | 46,596 Da |
NCBI Full Name: | Plasminogen activator inhibitor 2 |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
NCBI Official Symbol: | SERPINB2 |
NCBI Official Synonym Symbols: | PAI; PAI2; PAI-2; PLANH2; HsT1201 |
NCBI Protein Information: | plasminogen activator inhibitor 2; serpin B2; monocyte Arg-serpin; urokinase inhibitor; placental plasminogen activator inhibitor; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 |
UniProt Protein Name: | Plasminogen activator inhibitor 2 |
UniProt Synonym Protein Names: | Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor |
UniProt Gene Name: | SERPINB2 |
UniProt Entry Name: | PAI2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |