SEMG1 Antibody (PACO44141)
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주문- SKU:
- PACO44141
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SEMG1 Antibody (PACO44141) |
Antibody SKU: | PACO44141 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Semenogelin-1 protein (24-310AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: SEMG1 antibody at 4µg/ml + Mouse gonad tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 53, 46 kDa. Observed band size: 53 kDa.. |
Background: | Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.1 Publication |
Synonyms: | Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein], SEMG1, SEMG |
UniProt Protein Function: | SEMG1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Belongs to the semenogelin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Cancer Testis Antigen (CTA); Secreted Chromosomal Location of Human Ortholog: 20q12-q13.2 Cellular Component: extracellular region; extracellular space; nucleus; protein complex Molecular Function:metal ion binding; protein binding Biological Process: antibacterial humoral response; cellular protein metabolic process; coagulation; insemination; protein heterooligomerization |
NCBI Summary: | The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20. [provided by RefSeq, Feb 2016] |
UniProt Code: | P04279 |
NCBI GenInfo Identifier: | 134426 |
NCBI Gene ID: | 6406 |
NCBI Accession: | P04279.2 |
UniProt Secondary Accession: | P04279,Q53ZV0, Q53ZV1, Q53ZV2, Q6X4I9, Q6Y809, Q6Y822 Q6Y823, Q86U64, Q96QM3, |
UniProt Related Accession: | P04279 |
Molecular Weight: | 45,322 Da |
NCBI Full Name: | Semenogelin-1 |
NCBI Synonym Full Names: | semenogelin I |
NCBI Official Symbol: | SEMG1 |
NCBI Official Synonym Symbols: | SGI; SEMG; CT103; dJ172H20.2 |
NCBI Protein Information: | semenogelin-1 |
UniProt Protein Name: | Semenogelin-1 |
UniProt Synonym Protein Names: | Cancer/testis antigen 103; Semenogelin I; SGI |
Protein Family: | Semenogelin |
UniProt Gene Name: | SEMG1 |
UniProt Entry Name: | SEMG1_HUMAN |
Antibodies | ELISA Kits |
Anti-SEMG1 Antibody (CAB5487) | Human SEMG1 / Semenogelin-1 ELISA Kit |
SEMG1 Antibody (PACO12096) | Human Semenogelin-1 (SEMG1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |