SDC2 Antibody (PACO05001)
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주문- SKU:
- PACO05001
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | SDC2 Antibody (PACO05001) |
Antibody SKU: | PACO05001 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from the Internal region of human Syndecan-2. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | SDC2; HSPG1; Syndecan-2; SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD antigen CD362 |
UniProt Protein Function: | syndecan-2: a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Preferentially expressed in cells of mesenchymal origin. Is tyrosine phosphorylated and forms a complex with EphB2 in mouse brain. Plays a role in mediating adhesion and proliferation of colon carcinoma cells. |
UniProt Protein Details: | Protein type:Cell adhesion; Cell surface; Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 8q22-q23 Cellular Component: lysosomal lumen; cell soma; Golgi lumen; integral to membrane; plasma membrane; synapse Molecular Function:protein binding; PDZ domain binding Biological Process: axon guidance; phototransduction, visible light; extracellular matrix organization and biogenesis; wound healing; glycosaminoglycan metabolic process; dendrite morphogenesis; regulation of dendrite morphogenesis; pathogenesis; response to caffeine; chondroitin sulfate metabolic process; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; carbohydrate metabolic process; ephrin receptor signaling pathway; response to hypoxia; retinoid metabolic process |
NCBI Summary: | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008] |
UniProt Code: | P34741 |
NCBI GenInfo Identifier: | 158962336 |
NCBI Gene ID: | 6383 |
NCBI Accession: | P34741.2 |
UniProt Related Accession: | P34741 |
Molecular Weight: | |
NCBI Full Name: | Syndecan-2 |
NCBI Synonym Full Names: | syndecan 2 |
NCBI Official Symbol: | SDC2 |
NCBI Official Synonym Symbols: | HSPG; CD362; HSPG1; SYND2 |
NCBI Protein Information: | syndecan-2 |
UniProt Protein Name: | Syndecan-2 |
UniProt Synonym Protein Names: | Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD_antigen: CD362 |
Protein Family: | Syndecan |
UniProt Gene Name: | SDC2 |
UniProt Entry Name: | SDC2_HUMAN |