SCG2 Antibody (PACO46194)
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주문- SKU:
- PACO46194
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SCG2 Antibody (PACO46194) |
Antibody SKU: | PACO46194 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Secretogranin-2 protein (31-617AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO46194 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO46194 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO46194 at dilution of 1:100. |
Background: | Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. |
Synonyms: | Secretogranin-2 (Chromogranin-C) (Secretogranin II) (SgII) [Cleaved into: Secretoneurin (SN); Manserin], SCG2, CHGC |
UniProt Protein Function: | SCG2: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Belongs to the chromogranin/secretogranin protein family. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Motility/polarity/chemotaxis; Secreted; Cytokine; Secreted, signal peptide; Apoptosis Chromosomal Location of Human Ortholog: 2q35-q36 Cellular Component: extracellular space Molecular Function:chemoattractant activity; cytokine activity; protein binding Biological Process: angiogenesis; endothelial cell migration; eosinophil chemotaxis; induction of positive chemotaxis; inflammatory response; MAPKKK cascade; negative regulation of endothelial cell proliferation; positive chemotaxis; positive regulation of endothelial cell proliferation; protein secretion |
NCBI Summary: | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008] |
UniProt Code: | P13521 |
NCBI GenInfo Identifier: | 143811457 |
NCBI Gene ID: | 7857 |
NCBI Accession: | P13521.2 |
UniProt Secondary Accession: | P13521,Q53T11, Q8TBH3, B2R662, |
UniProt Related Accession: | P13521 |
Molecular Weight: | 70,941 Da |
NCBI Full Name: | Secretogranin-2 |
NCBI Synonym Full Names: | secretogranin II |
NCBI Official Symbol: | SCG2 |
NCBI Official Synonym Symbols: | SN; CHGC; EM66; SgII |
NCBI Protein Information: | secretogranin-2 |
UniProt Protein Name: | Secretogranin-2 |
UniProt Synonym Protein Names: | Chromogranin-C; Secretogranin II; SgII |
Protein Family: | Secretogranin |
UniProt Gene Name: | SCG2 |
UniProt Entry Name: | SCG2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |