S1PR3 Antibody (PACO19009)
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주문- SKU:
- PACO19009
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | S1PR3 Antibody (PACO19009) |
Antibody SKU: | PACO19009 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human S1PR3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 10%SDS-PAGE, Lysate: 50 μg, Lane: PC3 cells, Primary antibody: PACO19009(S1PR3 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
Background: | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
Synonyms: | Sphingosine-1-phosphate receptor 3 |
UniProt Protein Function: | S1PR3: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q22.1-q22.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; integrin binding; lipid binding; protein binding Biological Process: anatomical structure morphogenesis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation |
NCBI Summary: | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99500 |
NCBI GenInfo Identifier: | 42560554 |
NCBI Gene ID: | 1903 |
NCBI Accession: | Q99500.2 |
UniProt Secondary Accession: | Q99500,Q5SQD8, Q7Z5I2, |
UniProt Related Accession: | Q99500 |
Molecular Weight: | 42,250 Da |
NCBI Full Name: | Sphingosine 1-phosphate receptor 3 |
NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 3 |
NCBI Official Symbol: | S1PR3 |
NCBI Official Synonym Symbols: | EDG3; LPB3; S1P3; EDG-3 |
NCBI Protein Information: | sphingosine 1-phosphate receptor 3 |
UniProt Protein Name: | Sphingosine 1-phosphate receptor 3 |
UniProt Synonym Protein Names: | Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3 |
Protein Family: | Sphingosine 1-phosphate receptor |
UniProt Gene Name: | S1PR3 |
UniProt Entry Name: | S1PR3_HUMAN |
Antibodies | ELISA Kits |
Anti-S1PR3 Antibody (CAB15664) | Human S1P3 / EDG5 ELISA Kit |
S1PR3 Antibody (PACO02613) | Human Sphingosine 1-phosphate receptor 3 (S1PR3) ELISA Kit |
S1PR3 Antibody (PACO06446) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |