RUFY1 Antibody (PACO22584)
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주문- SKU:
- PACO22584
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RUFY1 Antibody (PACO22584) |
Antibody SKU: | PACO22584 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human RUFY1. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HeLa cells, using RUFY1 antibody. |
Background: | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. |
Synonyms: | FYVE-finger protein EIP1; Zinc finger FYVE domain-containing protein 12; La-binding protein 1; Rab4-interacting protein; |
UniProt Protein Function: | RUFY1: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 5q35.3 Cellular Component: intracellular membrane-bound organelle; early endosome membrane; cytoplasm; nucleus Molecular Function:protein binding; zinc ion binding; lipid binding; protein transporter activity Biological Process: protein transport; regulation of endocytosis; endocytosis |
NCBI Summary: | This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q96T51 |
NCBI GenInfo Identifier: | 94721332 |
NCBI Gene ID: | 80230 |
NCBI Accession: | NP_001035541.1 |
UniProt Secondary Accession: | Q96T51,Q59FF3, Q71S93, Q9H6I3, |
UniProt Related Accession: | Q96T51 |
Molecular Weight: | 79,818 Da |
NCBI Full Name: | RUN and FYVE domain-containing protein 1 isoform b |
NCBI Synonym Full Names: | RUN and FYVE domain containing 1 |
NCBI Official Symbol: | RUFY1 |
NCBI Official Synonym Symbols: | RABIP4; ZFYVE12 |
NCBI Protein Information: | RUN and FYVE domain-containing protein 1; la-binding protein 1; FYVE-finger protein EIP1; rab4-interacting protein; zinc finger FYVE domain-containing protein 12 |
UniProt Protein Name: | RUN and FYVE domain-containing protein 1 |
UniProt Synonym Protein Names: | FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; Zinc finger FYVE domain-containing protein 12 |
Protein Family: | RUN and FYVE domain-containing protein |
UniProt Gene Name: | RUFY1 |
UniProt Entry Name: | RUFY1_HUMAN |