UniProt Protein Function: | RPS4X: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Ribosomal; Translation; RNA-binding Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytosol; focal adhesion; membrane; nucleoplasm; polysome; ribonucleoprotein complex; ribosome; small ribosomal subunit Molecular Function:protein binding; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; multicellular organismal development; positive regulation of cell proliferation; positive regulation of translation; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
NCBI Summary: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P62701 |
NCBI GenInfo Identifier: | 50403628 |
NCBI Gene ID: | 6191 |
NCBI Accession: | P62701.2 |
UniProt Secondary Accession: | P62701,P12631, P12750, P27576, P55831, Q14727, Q6IPY4 |
UniProt Related Accession: | P62701 |
Molecular Weight: | 29,598 Da |
NCBI Full Name: | 40S ribosomal protein S4, X isoform |
NCBI Synonym Full Names: | ribosomal protein S4, X-linked |
NCBI Official Symbol: | RPS4X |
NCBI Official Synonym Symbols: | S4; CCG2; RPS4; SCAR; SCR10; DXS306 |
NCBI Protein Information: | 40S ribosomal protein S4, X isoform |
UniProt Protein Name: | 40S ribosomal protein S4, X isoform |
UniProt Synonym Protein Names: | SCR10; Single copy abundant mRNA protein |
Protein Family: | 40S ribosomal protein |
UniProt Gene Name: | RPS4X |
UniProt Entry Name: | RS4X_HUMAN |