RNF144B Antibody (PACO06729)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO06729
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RNF144B Antibody (PACO06729) |
Antibody SKU: | PACO06729 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from the Internal region of human p53RFP. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot analysis of RAT-MUSCLE HELA 293T AD293 cells using p53RFP Polyclonal Antibody. |
![]() | Western Blot analysis of HeLa cells using p53RFP Polyclonal Antibody. |
Synonyms: | RNF144B; IBRDC2; P53RFP; E3 ubiquitin-protein ligase RNF144B; IBR domain-containing protein 2; RING finger protein 144B; p53-inducible RING finger protein |
UniProt Protein Function: | RNF144B: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. Belongs to the RBR family. RNF144 subfamily. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase; Membrane protein, integral; EC 6.3.2.- Chromosomal Location of Human Ortholog: 6p22.3 Cellular Component: cytoplasm; cytosol; mitochondrial membrane; ubiquitin ligase complex Molecular Function:protein binding; ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activity Biological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process |
UniProt Code: | Q7Z419 |
NCBI GenInfo Identifier: | 57012811 |
NCBI Gene ID: | 255488 |
NCBI Accession: | Q7Z419.1 |
UniProt Secondary Accession: | Q7Z419,Q5TB85, Q6P4Q0, Q8N3R7, Q9BX38, B3KUA8, B4DZI2 |
UniProt Related Accession: | Q7Z419 |
Molecular Weight: | 23,856 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF144B |
NCBI Synonym Full Names: | ring finger protein 144B |
NCBI Official Symbol: | RNF144B |
NCBI Official Synonym Symbols: | PIR2; IBRDC2; p53RFP; bA528A10.3 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF144B |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF144B |
UniProt Synonym Protein Names: | IBR domain-containing protein 2; RING finger protein 144B; p53-inducible RING finger protein |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF144B |
UniProt Entry Name: | R144B_HUMAN |
Antibodies |
Anti-RNF144B Antibody (CAB13723) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |