RERE Antibody (PACO18706)
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주문- SKU:
- PACO18706
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RERE Antibody (PACO18706) |
Antibody SKU: | PACO18706 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human RERE |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO18706(RERE Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18706(RERE Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the atrophin family of arginine-glutamic acid, (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | arginine-glutamic acid, dipeptide (RE) repeats |
UniProt Protein Function: | RERE: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24). 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1p36.23 Molecular Function:poly-glutamine tract binding; protein binding Biological Process: NLS-bearing substrate import into nucleus |
NCBI Summary: | This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9P2R6 |
NCBI GenInfo Identifier: | 85540730 |
NCBI Gene ID: | 473 |
NCBI Accession: | Q9P2R6.2 |
UniProt Secondary Accession: | Q9P2R6,O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4 |
UniProt Related Accession: | Q9P2R6 |
Molecular Weight: | 109,048 Da |
NCBI Full Name: | Arginine-glutamic acid dipeptide repeats protein |
NCBI Synonym Full Names: | arginine-glutamic acid dipeptide repeats |
NCBI Official Symbol: | RERE |
NCBI Official Synonym Symbols: | ARG; ARP; DNB1; ATN1L; NEDBEH |
NCBI Protein Information: | arginine-glutamic acid dipeptide repeats protein |
UniProt Protein Name: | Arginine-glutamic acid dipeptide repeats protein |
UniProt Synonym Protein Names: | Atrophin-1-like protein; Atrophin-1-related protein |
Protein Family: | Arginine-glutamic acid dipeptide repeats protein |
UniProt Gene Name: | RERE |
UniProt Entry Name: | RERE_HUMAN |
Antibodies |
Anti-RERE Antibody (CAB15255) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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