RELT Antibody (PACO21924)
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주문- SKU:
- PACO21924
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RELT Antibody (PACO21924) |
Antibody SKU: | PACO21924 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from C-terminal of human TR19L. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from Jurkat cells, COLO205 cells, 293 cells and HepG2 cells, using TR19L antibody. |
Background: | Mediates activation of NF-kappa-B. May play a role in T-cell activation. Ota T., Nat. Genet. 36:40-45(2004). |
Synonyms: | Tumor necrosis factor receptor superfamily member 19L [Precursor]; Receptor expressed in lymphoid tissues; RELT; TNFRSF19L; |
UniProt Protein Function: | RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: integral to plasma membrane Molecular Function:tumor necrosis factor receptor activity Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide |
NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q969Z4 |
NCBI GenInfo Identifier: | 21264092 |
NCBI Gene ID: | 84957 |
NCBI Accession: | Q969Z4.1 |
UniProt Secondary Accession: | Q969Z4,Q86V34, Q96JU1, Q9BUX7, |
UniProt Related Accession: | Q969Z4 |
Molecular Weight: | 46,092 Da |
NCBI Full Name: | Tumor necrosis factor receptor superfamily member 19L |
NCBI Synonym Full Names: | RELT tumor necrosis factor receptor |
NCBI Official Symbol: | RELT |
NCBI Official Synonym Symbols: | TRLT; TNFRSF19L |
NCBI Protein Information: | tumor necrosis factor receptor superfamily member 19L |
UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 19L |
UniProt Synonym Protein Names: | Receptor expressed in lymphoid tissues |
Protein Family: | RELT-like protein |
UniProt Gene Name: | RELT |
UniProt Entry Name: | TR19L_HUMAN |