REC8 Antibody (PACO22406)
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주문- SKU:
- PACO22406
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | REC8 Antibody (PACO22406) |
Antibody SKU: | PACO22406 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human REC8. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from K562 cells, using REC8 antibody. |
Background: | Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity. |
Synonyms: | Meiotic recombination protein REC8 homolog; Cohesin Rec8p; REC8; REC8L1; |
NCBI Summary: | This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95072 |
NCBI GenInfo Identifier: | 14790109 |
NCBI Gene ID: | 9985 |
NCBI Accession: | BC010887 |
UniProt Secondary Accession: | O95072,Q658V5, Q6IA92, Q8WUV8, Q9BTF2, Q9NVQ9, A8K576 D3DS62, |
UniProt Related Accession: | O95072 |
Molecular Weight: | 60,774 Da |
NCBI Full Name: | Homo sapiens REC8 homolog (yeast), mRNA |
NCBI Synonym Full Names: | REC8 meiotic recombination protein |
NCBI Official Symbol: | REC8 |
NCBI Official Synonym Symbols: | Rec8p; REC8L1; HR21spB |
NCBI Protein Information: | meiotic recombination protein REC8 homolog |
UniProt Protein Name: | |
Protein Family: | Meiotic recombination protein |
UniProt Gene Name: |