RCVRN Antibody (PACO29432)
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주문- SKU:
- PACO29432
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RCVRN Antibody (PACO29432) |
Antibody SKU: | PACO29432 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Recoverin protein (2-200AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: RCVRN antibody at 2µg/ml + Mouse eye tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 24 kDa Observed band size: 24 kDa . |
Background: | Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. |
Synonyms: | Recoverin (Cancer-associated retinopathy protein) (Protein CAR), RCVRN, RCV1 |
UniProt Protein Function: | RCV1: Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. Belongs to the recoverin family. |
UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 17p13.1 Molecular Function:calcium ion binding; calcium sensitive guanylate cyclase activator activity Biological Process: phototransduction, visible light; positive regulation of guanylate cyclase activity; regulation of calcium ion transport; regulation of rhodopsin mediated signaling; rhodopsin mediated signaling; signal transduction; visual perception |
NCBI Summary: | This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008] |
UniProt Code: | P35243 |
NCBI GenInfo Identifier: | 464600 |
NCBI Gene ID: | 5957 |
NCBI Accession: | P35243.2 |
UniProt Secondary Accession: | P35243,Q53XL0, |
UniProt Related Accession: | P35243 |
Molecular Weight: | 23,130 Da |
NCBI Full Name: | Recoverin |
NCBI Synonym Full Names: | recoverin |
NCBI Official Symbol: | RCVRN |
NCBI Official Synonym Symbols: | RCV1 |
NCBI Protein Information: | recoverin |
UniProt Protein Name: | Recoverin |
UniProt Synonym Protein Names: | Cancer-associated retinopathy protein; Protein CAR |
Protein Family: | Recoverin |
UniProt Gene Name: | RCVRN |
UniProt Entry Name: | RECO_HUMAN |
Antibodies | ELISA Kits |
Anti-RCVRN Antibody (CAB6404) | Recoverin Colorimetric Cell-Based ELISA |
RCVRN Antibody (PACO03061) | |
RCVRN Antibody (PACO11782) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |