RBMY1A1 Antibody (PACO13805)
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주문- SKU:
- PACO13805
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RBMY1A1 Antibody (PACO13805) |
Antibody SKU: | PACO13805 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human RBMY1A1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A549 cells, Hela cells, PC3 cells, HepG2 cells, Primary antibody: PACO13805(RBMY1A1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
Background: | This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. |
Synonyms: | RNA binding motif protein, Y-linked, family 1, member A1 |
UniProt Protein Function: | RBMY1A1: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. |
UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Yq11.223 Molecular Function:mRNA binding; protein binding Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome Disease: Spermatogenic Failure, Y-linked, 2 |
NCBI Summary: | This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016] |
UniProt Code: | P0DJD3 |
NCBI GenInfo Identifier: | 1004170692 |
NCBI Gene ID: | 5940 |
NCBI Accession: | NP_001307873.1 |
UniProt Secondary Accession: | P0DJD3,Q15376, Q15377, Q15414, Q6NSB5, Q86VU6, Q8NHR0 |
UniProt Related Accession: | P0DJD3 |
Molecular Weight: | 55.4kD |
NCBI Full Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 isoform 2 |
NCBI Synonym Full Names: | RNA binding motif protein, Y-linked, family 1, member A1 |
NCBI Official Symbol: | RBMY1A1 |
NCBI Official Synonym Symbols: | RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C |
NCBI Protein Information: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
UniProt Protein Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
UniProt Synonym Protein Names: | RNA-binding motif protein 1; RNA-binding motif protein 2; Y chromosome RNA recognition motif 1; hRBMY |
Protein Family: | RNA-binding motif protein |
UniProt Gene Name: | RBMY1A1 |
Antibodies |
Anti-RBMY1A1 Antibody (CAB18376) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |