RARRES3 Antibody (PACO42518)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO42518
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RARRES3 Antibody (PACO42518) |
Antibody SKU: | PACO42518 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Retinoic acid, receptor responder protein 3 protein (1-133AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO42518 at dilution of 1:100. |
Background: | Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable. |
Synonyms: | Retinoic acid, receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein), RARRES3, RIG1 TIG3 |
UniProt Protein Function: | RARRES3: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable. Belongs to the H-rev107 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation; EC 3.1.1.- Chromosomal Location of Human Ortholog: 11q23 Molecular Function:phospholipase A2 activity; protein binding Biological Process: phospholipid metabolic process |
NCBI Summary: | Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UL19 |
NCBI GenInfo Identifier: | 20140910 |
NCBI Gene ID: | 5920 |
NCBI Accession: | Q9UL19.1 |
UniProt Secondary Accession: | Q9UL19,O95200, B2R599, B4DDW2, E7ENZ7, |
UniProt Related Accession: | Q9UL19 |
Molecular Weight: | 17,436 Da |
NCBI Full Name: | Retinoic acid receptor responder protein 3 |
NCBI Synonym Full Names: | retinoic acid receptor responder 3 |
NCBI Official Symbol: | RARRES3 |
NCBI Official Synonym Symbols: | RIG1; TIG3; HRSL4; HRASLS4; PLA1/2-3 |
NCBI Protein Information: | retinoic acid receptor responder protein 3 |
UniProt Protein Name: | Retinoic acid receptor responder protein 3 |
UniProt Synonym Protein Names: | HRAS-like suppressor 4; HRSL4; RAR-responsive protein TIG3; Retinoid-inducible gene 1 protein; Tazarotene-induced gene 3 protein |
Protein Family: | Retinoic acid receptor responder protein |
UniProt Gene Name: | RARRES3 |
UniProt Entry Name: | HRSL4_HUMAN |