RAP2B Antibody (PACO45257)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO45257
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RAP2B Antibody (PACO45257) |
Antibody SKU: | PACO45257 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ras-related protein Rap-2b protein (1-183AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO45257 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45257 at dilution of 1:100. |
Background: | Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. |
Synonyms: | Ras-related protein Rap-2b, RAP2B |
UniProt Protein Function: | RAP2B: Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. Belongs to the small GTPase superfamily. Ras family. |
UniProt Protein Details: | Protein type:G protein, monomeric, Ras; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: 3q25.2 Cellular Component: tight junction; membrane; recycling endosome membrane; plasma membrane; cytosol; lipid raft Molecular Function:protein domain specific binding; GDP binding; GTP binding Biological Process: platelet activation; microvillus biogenesis; signal transduction; positive regulation of protein amino acid autophosphorylation; negative regulation of cell migration; Rap protein signal transduction |
NCBI Summary: | This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008] |
UniProt Code: | P61225 |
NCBI GenInfo Identifier: | 47117762 |
NCBI Gene ID: | 5912 |
NCBI Accession: | P61225.1 |
UniProt Secondary Accession: | P61225,P17964, Q96EG5, Q9CXG0, |
UniProt Related Accession: | P61225 |
Molecular Weight: | 183 |
NCBI Full Name: | Ras-related protein Rap-2b |
NCBI Synonym Full Names: | RAP2B, member of RAS oncogene family |
NCBI Official Symbol: | RAP2B |
NCBI Protein Information: | ras-related protein Rap-2b; small GTP binding protein |
UniProt Protein Name: | Ras-related protein Rap-2b |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAP2B |
UniProt Entry Name: | RAP2B_HUMAN |