The Purified Mouse CD45.2 Monoclonal Antibody (Clone: 104-2, AGEL1513) offered by AssayGenie is a powerful tool for researchers studying CD45.2, a key protein involved in immune cell signaling and activation. This monoclonal antibody, developed specifically for mouse samples, is ideal for a wide range of applications in immunology research.CD45.2 is a cell surface marker that plays a crucial role in the regulation of immune responses and lymphocyte development. The monoclonal antibody 104-2, recognized for its high specificity and sensitivity, binds specifically to CD45.2, enabling accurate detection and analysis of this important protein in various experimental settings.
By targeting CD45.2, researchers can gain valuable insights into immune cell function, differentiation, and activation. This antibody's reliability and consistency make it a valuable tool for studies focusing on immunological processes, such as immune cell profiling, inflammation, and immune system disorders.With its high reactivity and specificity for mouse CD45.2, the Purified Mouse CD45.2 Monoclonal Antibody (Clone: 104-2, AGEL1513) from AssayGenie is a trusted reagent for researchers looking to advance their understanding of immune responses and immune cell function in a laboratory setting.
Product Title:
Purified Anti-Mouse CD45.2 Antibody [104.2]
SKU:
AGEL1513
Size:
25µg, 100µg
Clone No:
104.2
Synonyms:
Ly-5.2; LCA;
Host Species:
Mouse
Reactivity:
Mouse
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.