PTPN4 Antibody (PACO45553)
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주문- SKU:
- PACO45553
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PTPN4 Antibody (PACO45553) |
Antibody SKU: | PACO45553 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 protein (1-240AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45553 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO45553 at dilution of 1:100. |
Background: | May act at junctions between the membrane and the cytoskeleton. |
Synonyms: | Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1), PTPN4 |
UniProt Protein Function: | PTPN4: May act at junctions between the membrane and the cytoskeleton. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. |
UniProt Protein Details: | Protein type:Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.48 Chromosomal Location of Human Ortholog: 2q14.2 Cellular Component: internal side of plasma membrane; cytoskeleton; cytoplasm Molecular Function:protein binding; cytoskeletal protein binding; non-membrane spanning protein tyrosine phosphatase activity Biological Process: protein amino acid dephosphorylation |
NCBI Summary: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P29074 |
NCBI GenInfo Identifier: | 131531 |
NCBI Gene ID: | 5775 |
NCBI Accession: | P29074.1 |
UniProt Secondary Accession: | P29074,Q9UDA7, B2RBV8, |
UniProt Related Accession: | P29074 |
Molecular Weight: | 926 |
NCBI Full Name: | Tyrosine-protein phosphatase non-receptor type 4 |
NCBI Synonym Full Names: | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
NCBI Official Symbol: | PTPN4 |
NCBI Official Synonym Symbols: | MEG; PTPMEG; PTPMEG1 |
NCBI Protein Information: | tyrosine-protein phosphatase non-receptor type 4; PTPase-MEG1; megakaryocyte phosphatase; protein tyrosine phosphatase MEG1; protein-tyrosine phosphatase MEG1; megakaryocyte protein-tyrosine phosphatase |
UniProt Protein Name: | Tyrosine-protein phosphatase non-receptor type 4 |
UniProt Synonym Protein Names: | Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1 |
Protein Family: | Tyrosine-protein phosphatase non-receptor |
UniProt Gene Name: | PTPN4 |
UniProt Entry Name: | PTN4_HUMAN |