PTOV1 Antibody (PACO59185)
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주문- SKU:
- PACO59185
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PTOV1 Antibody (PACO59185) |
Antibody SKU: | PACO59185 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO59185 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of Hela cells with PACO59185 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | IHC image of PACO59185 diluted at 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. |
Synonyms: | Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2), PTOV1, acid, |
UniProt Protein Function: | PTOV1: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: nucleus |
NCBI Summary: | This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
UniProt Code: | Q86YD1 |
NCBI GenInfo Identifier: | 74762466 |
NCBI Gene ID: | 53635 |
NCBI Accession: | Q86YD1.1 |
UniProt Secondary Accession: | Q86YD1,Q6UXX7, Q96BU3, Q9HBN4, Q9NYL1, |
UniProt Related Accession: | Q86YD1 |
Molecular Weight: | 26,145 Da |
NCBI Full Name: | Prostate tumor-overexpressed gene 1 protein |
NCBI Synonym Full Names: | prostate tumor overexpressed 1 |
NCBI Official Symbol: | PTOV1 |
NCBI Official Synonym Symbols: | ACID2; PTOV-1 |
NCBI Protein Information: | prostate tumor-overexpressed gene 1 protein |
UniProt Protein Name: | Prostate tumor-overexpressed gene 1 protein |
UniProt Synonym Protein Names: | Activator interaction domain-containing protein 2 |
Protein Family: | Prostate tumor-overexpressed gene 1 protein |
UniProt Gene Name: | PTOV1 |
UniProt Entry Name: | PTOV1_HUMAN |
Antibodies |
Anti-PTOV1 Antibody (CAB16126) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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