PRICKLE2 Antibody (PACO44789)
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주문- SKU:
- PACO44789
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PRICKLE2 Antibody (PACO44789) |
Antibody SKU: | PACO44789 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Prickle-like protein 2 protein (615-844AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO44789 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO44789 at dilution of 1:100. |
Background: | cytoplasm, Wnt signaling pathway, planar cell polarity pathway |
Synonyms: | Prickle-like protein 2, PRICKLE2 |
UniProt Protein Function: | PRICKLE2: Defects in PRICKLE2 are the cause of progressive myoclonic epilepsy type 5 (EPM5). EPM5 is a neurodegenerative disorder characterized by myoclonic seizures and variable neurologic symptoms including cognitive decline and persistent movement abnormalities. Belongs to the prickle / espinas / testin family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: nuclear membrane; apicolateral plasma membrane; cytoplasm; lateral plasma membrane Molecular Function:zinc ion binding Biological Process: establishment and/or maintenance of epithelial cell polarity; neurite development Disease: Epilepsy, Progressive Myoclonic 5 |
NCBI Summary: | This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q7Z3G6 |
NCBI GenInfo Identifier: | 38524620 |
NCBI Gene ID: | 166336 |
NCBI Accession: | NP_942559 |
UniProt Related Accession: | Q7Z3G6 |
Molecular Weight: | 95kDa |
NCBI Full Name: | prickle-like protein 2 |
NCBI Synonym Full Names: | prickle planar cell polarity protein 2 |
NCBI Official Symbol: | PRICKLE2 |
NCBI Official Synonym Symbols: | EPM5 |
NCBI Protein Information: | prickle-like protein 2 |
UniProt Protein Name: | Prickle-like protein 2 |
Protein Family: | Prickle-like protein |
UniProt Gene Name: | PRICKLE2 |
UniProt Entry Name: | PRIC2_HUMAN |
Antibodies |
Anti-PRICKLE2 Antibody (CAB8023) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |