PRAF2 Antibody (PACO20374)
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주문- SKU:
- PACO20374
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PRAF2 Antibody (PACO20374) |
Antibody SKU: | PACO20374 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human PRAF2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20374(PRAF2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20374(PRAF2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | JM4 (Jena-Muenchen 4), also known as PRAF2 (PRA1 domain family, member 2), is a 178 amino acid, endosomal multi-pass membrane protein involved in vesicular trafficking and Endoplasmic reticulum/Golgi transport. As a member of the PRA1 family, JM4 contains four putative transmembrane (TM) domains, interacts with the CC chemokine receptor 5 (CCR5) and colocalizes with Calnexin in the ER and mannose 6-phosphate receptor (CD-MPR) in the Golgi apparatus. |
Synonyms: | PRA1 domain family, member 2 |
UniProt Protein Function: | PRAF2: May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis. Belongs to the PRA1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: integral to membrane; endosome membrane Biological Process: protein transport; L-glutamate transport |
UniProt Code: | O60831 |
NCBI GenInfo Identifier: | 6005794 |
NCBI Gene ID: | 11230 |
NCBI Accession: | NP_009144.1 |
UniProt Secondary Accession: | O60831,B2RD20, |
UniProt Related Accession: | O60831 |
Molecular Weight: | 19,258 Da |
NCBI Full Name: | PRA1 family protein 2 |
NCBI Synonym Full Names: | PRA1 domain family, member 2 |
NCBI Official Symbol: | PRAF2 |
NCBI Official Synonym Symbols: | JM4 |
NCBI Protein Information: | PRA1 family protein 2 |
UniProt Protein Name: | PRA1 family protein 2 |
UniProt Gene Name: | PRAF2 |
UniProt Entry Name: | PRAF2_HUMAN |
Antibodies | ELISA Kits |
Anti-PRAF2 Antibody (CAB18421) | JM4 Colorimetric Cell-Based ELISA Kit |
PRAF2 Antibody (PACO06775) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |