PPP2R3B Antibody (PACO22601)
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주문- SKU:
- PACO22601
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PPP2R3B Antibody (PACO22601) |
Antibody SKU: | PACO22601 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human P2R3B. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from K562 cells, using P2R3B antibody. |
Background: | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Synonyms: | NY-REN-8; P2R3B; PP2A B; PP2A; subunit B |
UniProt Protein Function: | PPP2R3B: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: Xp22.33; Yp11.3 Cellular Component: nucleoplasm; nucleus; protein phosphatase type 2A complex Molecular Function:phosphoprotein phosphatase activity; protein binding; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity Biological Process: cell cycle arrest; protein amino acid dephosphorylation |
NCBI Summary: | Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010] |
UniProt Code: | Q9Y5P8 |
NCBI GenInfo Identifier: | 158523346 |
NCBI Gene ID: | 28227 |
NCBI Accession: | Q9Y5P8.2 |
UniProt Secondary Accession: | Q9Y5P8,Q6P4G9, Q7RTT1, Q96H01, |
UniProt Related Accession: | Q9Y5P8 |
Molecular Weight: | 20,111 Da |
NCBI Full Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
NCBI Synonym Full Names: | protein phosphatase 2 regulatory subunit B''beta |
NCBI Official Symbol: | PPP2R3B |
NCBI Official Synonym Symbols: | PR48; NYREN8; PPP2R3L; PPP2R3LY |
NCBI Protein Information: | serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
UniProt Protein Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
UniProt Synonym Protein Names: | PP2A subunit B isoform PR48; Protein phosphatase 2A 48 kDa regulatory subunit |
Protein Family: | Serine/threonine-protein phosphatase |
UniProt Gene Name: | PPP2R3B |
UniProt Entry Name: | P2R3B_HUMAN |