PPP2R1B Antibody (PACO01355)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO01355
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PPP2R1B Antibody |
Antibody SKU: | PACO01355 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IHC:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the C-terminal region of human PP2A-ABeta. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | PPP2R1B; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta |
UniProt Protein Function: | PPP2R1B: The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Belongs to the phosphatase 2A regulatory subunit A family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 11q23.2 Cellular Component: lipid raft Molecular Function:protein binding Disease: Lung Cancer |
NCBI Summary: | This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] |
UniProt Code: | P30154 |
NCBI GenInfo Identifier: | 116241236 |
NCBI Gene ID: | 5519 |
NCBI Accession: | P30154.3 |
UniProt Secondary Accession: | P30154,O75620, Q8NHV8, A8MY67, B0YJ69, B4DGQ6, B4DK91 B4DWW5, F8W8G1, |
UniProt Related Accession: | P30154 |
Molecular Weight: | 52,214 Da |
NCBI Full Name: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
NCBI Synonym Full Names: | protein phosphatase 2 scaffold subunit Abeta |
NCBI Official Symbol: | PPP2R1B |
NCBI Official Synonym Symbols: | PR65B; PP2A-Abeta |
NCBI Protein Information: | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
UniProt Protein Name: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
UniProt Synonym Protein Names: | PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta |
UniProt Gene Name: | PPP2R1B |
UniProt Entry Name: | 2AAB_HUMAN |