PPM1K Antibody (PACO38242)
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주문- SKU:
- PACO38242
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PPM1K Antibody (PACO38242) |
Antibody SKU: | PACO38242 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Protein phosphatase 1K, mitochondrial protein (30-372AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate, Mouse skeletal muscle tissue. All lanes: PPM1K antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 41, 26, 17 kDa. Observed band size: 41 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO38242 at dilution of 1:100. |
Background: | Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. |
Synonyms: | Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C isoform kappa) (PP2C-kappa), PPM1K, PP2CM |
UniProt Protein Function: | PPM1K: Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q22.1 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:metal ion binding; protein binding; protein serine/threonine phosphatase activity Biological Process: branched chain family amino acid catabolic process; protein amino acid dephosphorylation Disease: Maple Syrup Urine Disease, Mild Variant |
NCBI Summary: | This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012] |
UniProt Code: | Q8N3J5 |
NCBI GenInfo Identifier: | 74750962 |
NCBI Gene ID: | 152926 |
NCBI Accession: | Q8N3J5.1 |
UniProt Secondary Accession: | Q8N3J5,Q05CT5, Q49AB5, Q4W5E6, Q56AN8, Q8IUZ7, Q8IXG7 Q8ND70, Q96NT4, B2RAZ1, |
UniProt Related Accession: | Q8N3J5 |
Molecular Weight: | 16,759 Da |
NCBI Full Name: | Protein phosphatase 1K, mitochondrial |
NCBI Synonym Full Names: | protein phosphatase, Mg2+/Mn2+ dependent 1K |
NCBI Official Symbol: | PPM1K |
NCBI Official Synonym Symbols: | BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07 |
NCBI Protein Information: | protein phosphatase 1K, mitochondrial |
UniProt Protein Name: | Protein phosphatase 1K, mitochondrial |
UniProt Synonym Protein Names: | PP2C domain-containing protein phosphatase 1K; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PTMP; Protein phosphatase 2C isoform kappa; PP2C-kappa |
Protein Family: | Protein phosphatase |
UniProt Gene Name: | PPM1K |
UniProt Entry Name: | PPM1K_HUMAN |