PPA2 Antibody (PACO59381)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO59381
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PPA2 Antibody (PACO59381) |
Antibody SKU: | PACO59381 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Inorganic pyrophosphatase 2, mitochondrial protein (180-298AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, Rat kidney tissue, Rat liver tissue, Mouse kidney tissue, Mouse liver tissue. All lanes: PPA2 antibody at 3.1µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38, 40, 35, 19, 26 kDa. Observed band size: 38 kDa. |
![]() | IHC image of PACO59381 diluted at 1:200 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function. |
Synonyms: | Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2), PPA2 |
UniProt Protein Function: | PPA2: is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Mitochondrial; Hydrolase; EC 3.6.1.1; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 4q25 Cellular Component: mitochondrial matrix Molecular Function:inorganic diphosphatase activity; magnesium ion binding; protein serine/threonine phosphatase activity Biological Process: tRNA aminoacylation for protein translation; dephosphorylation; gene expression |
NCBI Summary: | The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H2U2 |
NCBI GenInfo Identifier: | 77812678 |
NCBI Gene ID: | 27068 |
NCBI Accession: | NP_008834.3 |
UniProt Secondary Accession: | Q9H2U2,Q4W5E9, Q6PG51, Q8TBW0, Q96E55, Q9H0T0, Q9NX37 Q9P033, Q9ULX0, B4DLP7, F8WDN9, I6L9B6, |
UniProt Related Accession: | Q9H2U2 |
Molecular Weight: | 25,992 Da |
NCBI Full Name: | inorganic pyrophosphatase 2, mitochondrial isoform 2 |
NCBI Synonym Full Names: | pyrophosphatase (inorganic) 2 |
NCBI Official Symbol: | PPA2 |
NCBI Official Synonym Symbols: | HSPC124; SID6-306 |
NCBI Protein Information: | inorganic pyrophosphatase 2, mitochondrial |
UniProt Protein Name: | Inorganic pyrophosphatase 2, mitochondrial |
UniProt Synonym Protein Names: | Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; PPase 2 |
Protein Family: | Soluble inorganic pyrophosphatase |
UniProt Gene Name: | PPA2 |
UniProt Entry Name: | IPYR2_HUMAN |