POU2F2 Antibody (PACO23687)
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주문- SKU:
- PACO23687
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | POU2F2 Antibody (PACO23687) |
Antibody SKU: | PACO23687 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human OCT2 antibody. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence analysis of COS7 cells, using OCT2 antibody. |
![]() | Western blot analysis of extracts from JK cells (Lane 2), using OCT2 antiobdy. The lane on the left is treated with synthesized peptide. |
![]() | Western blot analysis of extracts from COS7 cells, using OCT2 antibody. |
Background: | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. |
Synonyms: | 41914; OTF2; OCTAMER-BINDING TRANSCRIPTION FACTOR 2; OTF LYMPHOID-SPECIFIC 2; |
UniProt Protein Function: | Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein domain specific binding; sequence-specific DNA binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response |
NCBI Summary: | The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P09086 |
NCBI GenInfo Identifier: | 123402 |
NCBI Gene ID: | 5452 |
NCBI Accession: | P09086.3 |
UniProt Secondary Accession: | P09086,Q16648, Q7M4M8, Q9BRS4, |
UniProt Related Accession: | P09086 |
Molecular Weight: | 400 |
NCBI Full Name: | POU domain, class 2, transcription factor 2 |
NCBI Synonym Full Names: | POU class 2 homeobox 2 |
NCBI Official Symbol: | POU2F2 |
NCBI Official Synonym Symbols: | OCT2; OTF2; Oct-2 |
NCBI Protein Information: | POU domain, class 2, transcription factor 2; OTF-2; homeobox protein; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 |
UniProt Protein Name: | POU domain, class 2, transcription factor 2 |
UniProt Synonym Protein Names: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2 |
Protein Family: | POU domain, class 2, transcription factor |
UniProt Gene Name: | POU2F2 |
UniProt Entry Name: | PO2F2_HUMAN |
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