POLI Antibody (PACO11348)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO11348
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | POLI Antibody (PACO11348) |
Antibody SKU: | PACO11348 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human POLI |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | polymerase (DNA directed) iota;POLI;RAD30B;RAD3OB ; |
UniProt Protein Function: | POLI: Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity. Belongs to the DNA polymerase type-Y family. |
UniProt Protein Details: | Protein type:EC 2.7.7.7; Transferase; DNA repair, damage Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; intracellular; nucleus Molecular Function:protein binding; metal ion binding; damaged DNA binding; DNA-directed DNA polymerase activity Biological Process: DNA repair; DNA replication |
UniProt Code: | Q9UNA4 |
NCBI GenInfo Identifier: | 327478565 |
NCBI Gene ID: | 11201 |
NCBI Accession: | Q9UNA4.3 |
UniProt Secondary Accession: | Q9UNA4,Q8N590, Q9H0S1, Q9NYH6, |
UniProt Related Accession: | Q9UNA4 |
Molecular Weight: | 740 |
NCBI Full Name: | DNA polymerase iota |
NCBI Synonym Full Names: | polymerase (DNA directed) iota |
NCBI Official Symbol: | POLI |
NCBI Official Synonym Symbols: | RAD30B; RAD3OB |
NCBI Protein Information: | DNA polymerase iota; eta2; RAD30 homolog B; polymerase (DNA-directed), iota |
UniProt Protein Name: | DNA polymerase iota |
UniProt Synonym Protein Names: | Eta2; RAD30 homolog B |
Protein Family: | Poliovirus receptor |
UniProt Gene Name: | POLI |
UniProt Entry Name: | POLI_HUMAN |