PODN Antibody (PACO03432)
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주문- SKU:
- PACO03432
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PODN Antibody |
Antibody SKU: | PACO03432 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the C-terminal region of human Podocan. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | PODN; SLRR5A; Podocan |
UniProt Protein Function: | PODN: Negatively regulates cell proliferation and cell migration. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1p32.3 Cellular Component: cytoplasm; extracellular space Molecular Function:collagen binding; protein kinase inhibitor activity Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity |
NCBI Summary: | The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q7Z5L7 |
NCBI GenInfo Identifier: | 118573110 |
NCBI Gene ID: | 127435 |
NCBI Accession: | Q7Z5L7.2 |
UniProt Secondary Accession: | Q7Z5L7,Q5VVZ2, Q5VVZ3, Q6PIR3, Q6UXL8, Q8N641, B4DKN5 B4E373, |
UniProt Related Accession: | Q7Z5L7 |
Molecular Weight: | 57,896 Da |
NCBI Full Name: | Podocan |
NCBI Synonym Full Names: | podocan |
NCBI Official Symbol: | PODN |
NCBI Official Synonym Symbols: | PCAN; SLRR5A |
NCBI Protein Information: | podocan |
UniProt Protein Name: | Podocan |
Protein Family: | Podocan |
UniProt Gene Name: | PODN |
UniProt Entry Name: | PODN_HUMAN |