PMVK Antibody (PACO11323)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO11323
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PMVK Antibody (PACO11323) |
Antibody SKU: | PACO11323 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human PMVK |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | phosphomevalonate kinase;PMVK;HUMPMKI;PMK;PMKA;PMKASE ; |
UniProt Protein Function: | PMVK: Induced by sterol. Monomer. |
UniProt Protein Details: | Protein type:Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 2.7.4.2; Kinase, other Chromosomal Location of Human Ortholog: 1q22 Cellular Component: membrane; peroxisome; cytosol Molecular Function:phosphomevalonate kinase activity; ATP binding Biological Process: isopentenyl diphosphate biosynthetic process, mevalonate pathway; sterol biosynthetic process; phosphorylation; cholesterol biosynthetic process |
NCBI Summary: | This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q15126 |
NCBI GenInfo Identifier: | 3024422 |
NCBI Gene ID: | 10654 |
NCBI Accession: | Q15126.3 |
UniProt Secondary Accession: | Q15126,Q5TZW9, |
UniProt Related Accession: | Q15126 |
Molecular Weight: | 21,995 Da |
NCBI Full Name: | Phosphomevalonate kinase |
NCBI Synonym Full Names: | phosphomevalonate kinase |
NCBI Official Symbol: | PMVK |
NCBI Official Synonym Symbols: | PMK; PMKA; PMKASE; HUMPMKI |
NCBI Protein Information: | phosphomevalonate kinase; hPMK |
UniProt Protein Name: | Phosphomevalonate kinase |
UniProt Gene Name: | PMVK |
UniProt Entry Name: | PMVK_HUMAN |