PLXNA4 Antibody (PACO40462)
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주문- SKU:
- PACO40462
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PLXNA4 Antibody (PACO40462) |
Antibody SKU: | PACO40462 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Plexin-A4 protein (24-522AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: PLXNA4 antibody at 3µg/ml + A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 213, 56, 59, 40 kDa. Observed band size: 56 kDa. |
Background: | Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
Synonyms: | Plexin-A4, PLXNA4, KIAA1550 PLXNA4A PLXNA4B |
UniProt Protein Function: | PLXNA4: Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Interacts with NRP1 and NRP2. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 7q32.3 Cellular Component: integral to membrane; plasma membrane; intracellular Molecular Function:semaphorin receptor activity Biological Process: facial nerve structural organization; trigeminal nerve structural organization; axon guidance; sympathetic nervous system development; anterior commissure morphogenesis; glossopharyngeal nerve morphogenesis; regulation of axon extension involved in axon guidance; postganglionic parasympathetic nervous system development; regulation of negative chemotaxis; vagus nerve morphogenesis; chemorepulsion of branchiomotor axon |
UniProt Code: | Q9HCM2 |
NCBI GenInfo Identifier: | 108860890 |
NCBI Gene ID: | 91584 |
NCBI Accession: | Q9HCM2.4 |
UniProt Secondary Accession: | Q9HCM2,Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4 A4D1N6, E9PAM2, |
UniProt Related Accession: | Q9HCM2 |
Molecular Weight: | 39,312 Da |
NCBI Full Name: | Plexin-A4 |
NCBI Synonym Full Names: | plexin A4 |
NCBI Official Symbol: | PLXNA4 |
NCBI Official Synonym Symbols: | PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003 |
NCBI Protein Information: | plexin-A4 |
UniProt Protein Name: | Plexin-A4 |
Protein Family: | Plexin |
UniProt Gene Name: | PLXNA4 |
UniProt Entry Name: | PLXA4_HUMAN |
Antibodies |
Anti-Plexin-A4 Antibody (CAB9990) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |