PLS3 Antibody (PACO16872)
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주문- SKU:
- PACO16872
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PLS3 Antibody (PACO16872) |
Antibody SKU: | PACO16872 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human PLS3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO16872(PLS3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: PACO16872(PLS3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16872(PLS3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). |
Synonyms: | plastin 3 |
UniProt Protein Function: | PLS3: Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: Xq23 Cellular Component: cytoplasm Molecular Function:calcium ion binding; actin binding Disease: Bone Mineral Density Quantitative Trait Locus 18 |
UniProt Code: | P13797 |
NCBI GenInfo Identifier: | 226694201 |
NCBI Gene ID: | |
NCBI Accession: | P13797.4 |
Molecular Weight: | ~ 71kDa |
NCBI Full Name: | Plastin-3 |
UniProt Protein Name: | Plastin-3 |
UniProt Synonym Protein Names: | T-plastin |
Protein Family: | Plastin |
UniProt Gene Name: | PLS3 |
UniProt Entry Name: | PLST_HUMAN |