PLD3 Antibody (PACO49882)
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주문- SKU:
- PACO49882
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PLD3 Antibody (PACO49882) |
Antibody SKU: | PACO49882 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phospholipase D3 protein (70-176AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO49882 at dilution of 1:100. |
![]() | Immunofluorescent analysis of Hela cells using PACO49882 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May be involved in APP processing. |
Synonyms: | Phospholipase D3 (PLD 3) (EC 3.1.4.4) (Choline phosphatase 3) (HindIII K4L homolog) (Hu-K4) (Phosphatidylcholine-hydrolyzing phospholipase D3), PLD3 |
UniProt Protein Function: | PLD3: Belongs to the phospholipase D family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Phospholipase; EC 3.1.4.4; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: endoplasmic reticulum membrane; integral to membrane Molecular Function:phospholipase D activity; protein binding Biological Process: glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylglycerol biosynthetic process; phospholipid metabolic process Disease: Alzheimer Disease 19 |
NCBI Summary: | This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014] |
UniProt Code: | Q8IV08 |
NCBI GenInfo Identifier: | 605052028 |
NCBI Gene ID: | 23646 |
NCBI Accession: | NP_001278240.1 |
UniProt Secondary Accession: | Q8IV08,Q92853, Q9BW87, |
UniProt Related Accession: | Q8IV08 |
Molecular Weight: | 54,705 Da |
NCBI Full Name: | phospholipase D3 |
NCBI Synonym Full Names: | phospholipase D family member 3 |
NCBI Official Symbol: | PLD3 |
NCBI Official Synonym Symbols: | AD19; HUK4; HU-K4 |
NCBI Protein Information: | phospholipase D3 |
UniProt Protein Name: | Phospholipase D3 |
UniProt Synonym Protein Names: | Choline phosphatase 3; HindIII K4L homolog; Hu-K4; Phosphatidylcholine-hydrolyzing phospholipase D3 |
Protein Family: | Phospholipase |
UniProt Gene Name: | PLD3 |
UniProt Entry Name: | PLD3_HUMAN |
Antibodies | ELISA Kits |
Anti-PLD3 Antibody (CAB18438) | Human Phospholipase D3 (PLD3) ELISA Kit |
PLD3 Antibody (PACO03734) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |