Phospho-GYS1 (S645) Antibody (PACO02805)
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주문- SKU:
- PACO02805
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-GYS1 (S645) Antibody |
Antibody SKU: | PACO02805 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human Glycogen synthase 1 around the phosphorylation site of S645. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GYS1; GYS; Glycogen [starch] synthase; muscle |
UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | P13807 |
NCBI GenInfo Identifier: | 1351366 |
NCBI Gene ID: | 2997 |
NCBI Accession: | P13807.2 |
UniProt Secondary Accession: | P13807,Q9BTT9, |
UniProt Related Accession: | P13807 |
Molecular Weight: | 737 |
NCBI Full Name: | Glycogen |
NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
NCBI Official Symbol: | GYS1 |
NCBI Official Synonym Symbols: | GSY; GYS |
NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
UniProt Protein Name: | Glycogen [starch] synthase, muscle |
Protein Family: | Glycogen [starch] synthase |
UniProt Gene Name: | GYS1 |
UniProt Entry Name: | GYS1_HUMAN |