Phospho-APLF (S116) Antibody (PACO03612)
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주문- SKU:
- PACO03612
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-APLF (S116) Antibody |
Antibody SKU: | PACO03612 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from human APLF around the phosphorylation site of S116. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1 |
UniProt Protein Function: | Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. |
NCBI Summary: | C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8IW19 |
NCBI GenInfo Identifier: | 27734905 |
NCBI Gene ID: | 200558 |
NCBI Accession: | NP_775816.1 |
UniProt Secondary Accession: | Q8IW19,Q53P47, Q53PB9, Q53QU0, A8K476, |
UniProt Related Accession: | Q8IW19 |
Molecular Weight: | |
NCBI Full Name: | aprataxin and PNK-like factor |
NCBI Synonym Full Names: | aprataxin and PNKP like factor |
NCBI Official Symbol: | APLF |
NCBI Official Synonym Symbols: | APFL; PALF; Xip1; ZCCHH1; C2orf13 |
NCBI Protein Information: | aprataxin and PNK-like factor |
UniProt Protein Name: | Aprataxin and PNK-like factor |
UniProt Synonym Protein Names: | Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1 |
Protein Family: | Aprataxin and PNK-like factor |
UniProt Gene Name: | APLF |