PFDN1 Antibody (PACO28358)
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주문- SKU:
- PACO28358
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PFDN1 Antibody (PACO28358) |
Antibody SKU: | PACO28358 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Prefoldin subunit 1 protein (2-122AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO28358 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO28358 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | PFDN1 is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. PFDN1 may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for non native proteins. |
Synonyms: | Prefoldin subunit 1, PFDN1, PFD1 |
UniProt Protein Function: | PFDN1: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family. |
UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 5q31 Molecular Function:transcription factor activity Biological Process: cell cycle |
NCBI Summary: | This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60925 |
NCBI GenInfo Identifier: | 22261811 |
NCBI Gene ID: | 5201 |
NCBI Accession: | O60925.2 |
UniProt Secondary Accession: | O60925,Q53F95, Q96EX6, B2RD02, |
UniProt Related Accession: | O60925 |
Molecular Weight: | 14,210 Da |
NCBI Full Name: | Prefoldin subunit 1 |
NCBI Synonym Full Names: | prefoldin subunit 1 |
NCBI Official Symbol: | PFDN1 |
NCBI Official Synonym Symbols: | PDF; PFD1 |
NCBI Protein Information: | prefoldin subunit 1 |
UniProt Protein Name: | Prefoldin subunit 1 |
Protein Family: | Prefoldin |
UniProt Gene Name: | PFDN1 |
UniProt Entry Name: | PFD1_HUMAN |
Antibodies | ELISA Kits |
Anti-PFDN1 Antibody (CAB8681) | PFDN1 Colorimetric Cell-Based ELISA |
PFDN1 Antibody (PACO04579) | |
PFDN1 Antibody (PACO11179) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |