PELO Antibody (PACO40338)
- SKU:
- PACO40338
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PELO Antibody (PACO40338) |
Antibody SKU: | PACO40338 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein pelota homolog protein (1-385AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO40338 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO40338 at dilution of 1:100. |
Background: | Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). |
Synonyms: | Protein pelota homolog (EC 3.1.-.-), PELO |
UniProt Protein Function: | PELO: Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. |
UniProt Protein Details: | Protein type:EC 3.1.-.-; Hydrolase Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: cytoplasm; nucleus Molecular Function:endonuclease activity; metal ion binding Biological Process: cell proliferation; cell division; cell cycle; chromosome organization and biogenesis |
NCBI Summary: | This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BRX2 |
NCBI GenInfo Identifier: | 322510057 |
NCBI Gene ID: | 53918 |
NCBI Accession: | Q9BRX2.2 |
UniProt Secondary Accession: | Q9BRX2,Q9GZS6, Q9Y306, |
UniProt Related Accession: | Q9BRX2 |
Molecular Weight: | 385 |
NCBI Full Name: | Protein pelota homolog |
NCBI Synonym Full Names: | pelota homolog (Drosophila) |
NCBI Official Symbol: | PELO |
NCBI Official Synonym Symbols: | CGI-17; PRO1770 |
NCBI Protein Information: | protein pelota homolog |
UniProt Protein Name: | Protein pelota homolog |
Protein Family: | Pelovaterin |
UniProt Gene Name: | PELO |
UniProt Entry Name: | PELO_HUMAN |
Antibodies | ELISA Kits |
Anti-PELO Antibody (CAB4776) | Human PELO (Protein pelota homolog) ELISA Kit (HUFI07273) |
PELO Antibody (PACO11166) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |