PECAM1 Antibody (PACO18342)
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주문- SKU:
- PACO18342
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PECAM1 Antibody (PACO18342) |
Antibody SKU: | PACO18342 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human PECAM1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18342(PECAM1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane: Jurkat cells, Primary antibody: PACO18342(PECAM1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO18342(PECAM1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. |
Synonyms: | Platelet/endothelial cell adhesion molecule 1 |
UniProt Protein Function: | PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: cell junction; extracellular space; integral to membrane; lipid raft; plasma membrane; platelet alpha granule membrane Molecular Function:protein binding Biological Process: blood coagulation; cell adhesion; cell recognition; diapedesis; extracellular matrix organization and biogenesis; leukocyte migration; phagocytosis; platelet activation; platelet degranulation; signal transduction |
NCBI Summary: | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010] |
UniProt Code: | P16284 |
NCBI GenInfo Identifier: | 129747 |
NCBI Gene ID: | 5175 |
NCBI Accession: | P16284.1 |
UniProt Secondary Accession: | P16284,Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7 Q9NPG9, Q9NQS9, Q9NQT0, A8K3S7, D3DU31, |
UniProt Related Accession: | P16284 |
Molecular Weight: | 81,378 Da |
NCBI Full Name: | Platelet endothelial cell adhesion molecule |
NCBI Synonym Full Names: | platelet and endothelial cell adhesion molecule 1 |
NCBI Official Symbol: | PECAM1 |
NCBI Official Synonym Symbols: | CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM |
NCBI Protein Information: | platelet endothelial cell adhesion molecule |
UniProt Protein Name: | Platelet endothelial cell adhesion molecule |
UniProt Synonym Protein Names: | EndoCAM; GPIIA'; PECA1; CD_antigen: CD31 |
Protein Family: | Platelet endothelial cell adhesion molecule |
UniProt Gene Name: | PECAM1 |
UniProt Entry Name: | PECA1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |