PCDHA6 Antibody (PACO21024)
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주문- SKU:
- PACO21024
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PCDHA6 Antibody (PACO21024) |
Antibody SKU: | PACO21024 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human PCDHA6 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO21024(PCDHA6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene is a member of the protocadherin α gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The α gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |
Synonyms: | protocadherin α 6 |
UniProt Code: | Q9UN73 |
NCBI GenInfo Identifier: | 13878423 |
NCBI Gene ID: | 56142 |
NCBI Accession: | Q9UN73.1 |
UniProt Secondary Accession: | Q9UN73,O75283, Q9NRT8, |
UniProt Related Accession: | Q9UN73 |
Molecular Weight: | 950 |
NCBI Full Name: | Protocadherin alpha-6 |
NCBI Synonym Full Names: | protocadherin alpha 6 |
NCBI Official Symbol: | PCDHA6 |
NCBI Official Synonym Symbols: | CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6 |
NCBI Protein Information: | protocadherin alpha-6; PCDH-alpha-6; KIAA0345-like 8 |
UniProt Protein Name: | Protocadherin alpha-6 |
Protein Family: | Protocadherin |
UniProt Gene Name: | PCDHA6 |
UniProt Entry Name: | PCDA6_HUMAN |