P2RX2 Antibody (PACO20151)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO20151
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | P2RX2 Antibody (PACO20151) |
Antibody SKU: | PACO20151 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human P2RX2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20151(P2RX2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Mouse brain tissue, Primary antibody: PACO20151(P2RX2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20151(P2RX2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Synonyms: | purinergic receptor P2X, ligand-gated ion channel, 2 |
UniProt Protein Function: | P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Channel, ligand-gated; Membrane protein, multi-pass; Membrane protein, integral; Channel, cation Chromosomal Location of Human Ortholog: 12q24.33 Cellular Component: presynaptic membrane; cell surface; cell soma; integral to plasma membrane; apical plasma membrane; postsynaptic density; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex Molecular Function:identical protein binding; zinc ion binding; mercury ion binding; drug binding; cadmium ion binding; ligand-gated ion channel activity; phosphoinositide binding; purinergic nucleotide receptor activity; nickel ion binding; copper ion binding; cobalt ion binding; ATP binding; ATP-gated cation channel activity Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; protein heterooligomerization; generation of action potential; skeletal muscle fiber development; positive regulation of calcium-mediated signaling; detection of hypoxic conditions in blood by carotid body chemoreceptors; response to carbohydrate stimulus; response to ATP; behavioral response to pain; sensory perception of sound; response to hypoxia; neuromuscular synaptic transmission; protein homooligomerization; neuromuscular junction development Disease: Deafness, Autosomal Dominant 41 |
NCBI Summary: | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q9UBL9 |
NCBI GenInfo Identifier: | 12643353 |
NCBI Gene ID: | 22953 |
NCBI Accession: | Q9UBL9.1 |
UniProt Secondary Accession: | Q9UBL9,Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7 A6NGB4, A6NH93, A6NHC2, A6NHU3, A6NIG9, |
UniProt Related Accession: | Q9UBL9 |
Molecular Weight: | 471 |
NCBI Full Name: | P2X purinoceptor 2 |
NCBI Synonym Full Names: | purinergic receptor P2X, ligand-gated ion channel, 2 |
NCBI Official Symbol: | P2RX2 |
NCBI Official Synonym Symbols: | P2X2; DFNA41 |
NCBI Protein Information: | P2X purinoceptor 2; ATP receptor; P2X Receptor, subunit 2 |
UniProt Protein Name: | P2X purinoceptor 2 |
UniProt Synonym Protein Names: | ATP receptor; Purinergic receptor |
Protein Family: | P2X purinoceptor |
UniProt Gene Name: | P2RX2 |
UniProt Entry Name: | P2RX2_HUMAN |
Antibodies |
Anti-P2RX2 Antibody (CAB7078) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |