OSGEP Antibody (PACO44667)
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주문- SKU:
- PACO44667
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | OSGEP Antibody (PACO44667) |
Antibody SKU: | PACO44667 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Probable tRNA N6-adenosine threonylcarbamoyltransferase protein (1-335AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: OSGEP antibody at 3.18µg/ml. Lane 1: 293T whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: Raji whole cell lysate. Lane 4: PC-3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44667 at dilution of 1:100. |
Background: | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. |
Synonyms: | Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP), OSGEP, GCPL1 |
UniProt Protein Function: | OSGEP: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Belongs to the KAE1 / YgjD family. |
UniProt Protein Details: | Protein type:Protease; EC 2.6.99.4 Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: cytoplasm; nucleus Molecular Function:metal ion binding; transferase activity, transferring groups other than amino-acyl groups |
UniProt Code: | Q9NPF4 |
NCBI GenInfo Identifier: | 47605574 |
NCBI Gene ID: | 55644 |
NCBI Accession: | Q9NPF4.1 |
UniProt Secondary Accession: | Q9NPF4,Q6IAC3, |
UniProt Related Accession: | Q9NPF4 |
Molecular Weight: | 335 |
NCBI Full Name: | Probable tRNA N6-adenosine threonylcarbamoyltransferase |
NCBI Synonym Full Names: | O-sialoglycoprotein endopeptidase |
NCBI Official Symbol: | OSGEP |
NCBI Official Synonym Symbols: | KAE1; GCPL1; OSGEP1; PRSMG1 |
NCBI Protein Information: | probable tRNA N6-adenosine threonylcarbamoyltransferase; OSGEP; hOSGEP; t(6)A synthase; N6-L-threonylcarbamoyladenine synthase; probable O-sialoglycoprotein endopeptidase; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP |
UniProt Protein Name: | Probable tRNA N6-adenosine threonylcarbamoyltransferase |
UniProt Synonym Protein Names: | N6-L-threonylcarbamoyladenine synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP |
Protein Family: | Probable tRNA N6-adenosine threonylcarbamoyltransferase |
UniProt Gene Name: | OSGEP |
UniProt Entry Name: | OSGEP_HUMAN |