OGN Antibody (PACO01994)
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주문- SKU:
- PACO01994
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | OGN Antibody |
Antibody SKU: | PACO01994 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the C-terminal region of human Osteoglycin. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | OGN; OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF |
UniProt Protein Function: | OGN: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9q22 Cellular Component: extracellular matrix; extracellular space; lysosomal lumen; proteinaceous extracellular matrix; Golgi lumen; extracellular region; vesicle Molecular Function:protein binding; growth factor activity Biological Process: keratan sulfate metabolic process; glycosaminoglycan metabolic process; negative regulation of smooth muscle cell proliferation; keratan sulfate biosynthetic process; carbohydrate metabolic process; pathogenesis; keratan sulfate catabolic process |
NCBI Summary: | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
UniProt Code: | P20774 |
NCBI GenInfo Identifier: | 129078 |
NCBI Gene ID: | 4969 |
NCBI Accession: | P20774.1 |
UniProt Related Accession: | P20774 |
Molecular Weight: | |
NCBI Full Name: | Mimecan |
NCBI Synonym Full Names: | osteoglycin |
NCBI Official Symbol: | OGN |
NCBI Official Synonym Symbols: | OG; OIF; SLRR3A |
NCBI Protein Information: | mimecan |
UniProt Protein Name: | Mimecan |
UniProt Synonym Protein Names: | Osteoglycin; Osteoinductive factor; OIF |
Protein Family: | Mimecan |
UniProt Gene Name: | OGN |
UniProt Entry Name: | MIME_HUMAN |