NTSR1 Antibody (PACO18298)
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주문- SKU:
- PACO18298
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | NTSR1 Antibody (PACO18298) |
Antibody SKU: | PACO18298 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human NTSR1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat cells, 231 cells, Primary antibody: PACO18298(NTSR1 Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. |
Background: | Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. |
Synonyms: | neurotensin receptor 1 (high affinity) |
UniProt Protein Function: | NTSR1: Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 20q13 Cellular Component: cell surface; dendritic shaft; dendritic spine; endoplasmic reticulum; Golgi apparatus; integral to plasma membrane; internal side of plasma membrane; lipid raft; mitochondrion; perikaryon; plasma membrane; terminal button Molecular Function:G-protein coupled receptor activity; neurotensin receptor activity, G-protein coupled; protein binding; protein heterodimerization activity; protein homodimerization activity; protein N-terminus binding Biological Process: adult locomotory behavior; detection of temperature stimulus involved in sensory perception of pain; G-protein coupled receptor protein signaling pathway; learning; negative regulation of apoptosis; negative regulation of release of sequestered calcium ion into cytosol; negative regulation of systemic arterial blood pressure; neuropeptide signaling pathway; positive regulation of apoptosis; positive regulation of gamma-aminobutyric acid secretion; positive regulation of glutamate secretion; positive regulation of release of sequestered calcium ion into cytosol; regulation of respiratory gaseous exchange; regulation of sensory perception of pain; response to lipid; synaptic transmission; thermoregulation |
NCBI Summary: | Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008] |
UniProt Code: | P30989 |
NCBI GenInfo Identifier: | 62297312 |
NCBI Gene ID: | 4923 |
NCBI Accession: | P30989.2 |
UniProt Secondary Accession: | P30989,Q9H4H1, Q9H4T5, |
UniProt Related Accession: | P30989 |
Molecular Weight: | 46,259 Da |
NCBI Full Name: | Neurotensin receptor type 1 |
NCBI Synonym Full Names: | neurotensin receptor 1 (high affinity) |
NCBI Official Symbol: | NTSR1 |
NCBI Official Synonym Symbols: | NTR |
NCBI Protein Information: | neurotensin receptor type 1 |
UniProt Protein Name: | Neurotensin receptor type 1 |
UniProt Synonym Protein Names: | High-affinity levocabastine-insensitive neurotensin receptor; NTRH |
Protein Family: | Neurotensin receptor |
UniProt Gene Name: | NTSR1 |
UniProt Entry Name: | NTR1_HUMAN |