NR2F2 Antibody (PACO20126)
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주문- SKU:
- PACO20126
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | NR2F2 Antibody (PACO20126) |
Antibody SKU: | PACO20126 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human NR2F2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20126(NR2F2 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute. |
Background: | This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. |
Synonyms: | nuclear receptor subfamily 2, group F, member 2 |
UniProt Protein Function: | NR2F2: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Interacts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2. Ubiquitous. Belongs to the nuclear hormone receptor family. NR2 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor Chromosomal Location of Human Ortholog: 15q26.2 Cellular Component: nucleus Molecular Function:ligand-dependent nuclear receptor activity; protein binding; protein homodimerization activity; retinoic acid binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity Biological Process: lipid metabolic process; negative regulation of cyclin-dependent protein kinase activity; negative regulation of endothelial cell proliferation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; signal transduction Disease: Congenital Heart Defects, Multiple Types, 4 |
NCBI Summary: | This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
UniProt Code: | P24468 |
NCBI GenInfo Identifier: | 114203 |
NCBI Gene ID: | 7026 |
NCBI Accession: | P24468.1 |
UniProt Secondary Accession: | P24468,Q03754, Q3KQR7, B4DQJ2, B6ZGU1, |
UniProt Related Accession: | P24468 |
Molecular Weight: | 46kDa |
NCBI Full Name: | COUP transcription factor 2 |
NCBI Synonym Full Names: | nuclear receptor subfamily 2 group F member 2 |
NCBI Official Symbol: | NR2F2 |
NCBI Official Synonym Symbols: | ARP1; CHTD4; NF-E3; NR2F1; SVP40; COUPTFB; TFCOUP2; COUPTFII |
NCBI Protein Information: | COUP transcription factor 2 |
UniProt Protein Name: | COUP transcription factor 2 |
UniProt Synonym Protein Names: | Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2 |
Protein Family: | COUP transcription factor |
UniProt Gene Name: | NR2F2 |