NPFFR2 Antibody (PACO63931)
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주문- SKU:
- PACO63931
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NPFFR2 Antibody (PACO63931) |
Antibody SKU: | PACO63931 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Peptide sequence from Human Neuropeptide FF receptor 2 protein (23-43AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of U251 cells with PACO63931 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Synonyms: | Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor), NPFFR2, GPR74 NPFF2 NPGPR |
UniProt Protein Function: | NPFFR2: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 4q21 Cellular Component: actin cytoskeleton; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide receptor activity; peptide binding Biological Process: cellular response to hormone stimulus; detection of abiotic stimulus; G-protein coupled receptor protein signaling pathway; synaptic transmission |
NCBI Summary: | This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
UniProt Code: | Q9Y5X5 |
NCBI GenInfo Identifier: | 13878604 |
NCBI Gene ID: | 10886 |
NCBI Accession: | Q9Y5X5.2 |
UniProt Secondary Accession: | Q9Y5X5,Q96RV1, Q9NR49, |
UniProt Related Accession: | Q9Y5X5 |
Molecular Weight: | 15,055 Da |
NCBI Full Name: | Neuropeptide FF receptor 2 |
NCBI Synonym Full Names: | neuropeptide FF receptor 2 |
NCBI Official Symbol: | NPFFR2 |
NCBI Official Synonym Symbols: | GPR74; NPFF2; NPGPR; HLWAR77 |
NCBI Protein Information: | neuropeptide FF receptor 2 |
UniProt Protein Name: | Neuropeptide FF receptor 2 |
UniProt Synonym Protein Names: | G-protein coupled receptor 74; G-protein coupled receptor HLWAR77; Neuropeptide G-protein coupled receptor |
Protein Family: | Neuropeptide FF receptor |
UniProt Gene Name: | NPFFR2 |
UniProt Entry Name: | NPFF2_HUMAN |
Antibodies | ELISA Kits |
Anti-NPFFR2 Antibody (CAB10664) | Human NPFFR2 / Neuropeptide FF receptor 3 ELISA Kit |
Human Neuropeptide FF receptor 2 (NPFFR2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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