NOX3 Antibody (PACO20117)
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주문- SKU:
- PACO20117
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NOX3 Antibody (PACO20117) |
Antibody SKU: | PACO20117 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human NOX3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20117(NOX3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20117(NOX3 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20117(NOX3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. |
Synonyms: | NADPH oxidase 3 |
UniProt Protein Function: | NOX3: NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Oxidoreductase; EC 1.6.3.-; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: plasma membrane |
NCBI Summary: | This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009] |
UniProt Code: | Q9HBY0 |
NCBI GenInfo Identifier: | 74752785 |
NCBI Gene ID: | 50508 |
NCBI Accession: | Q9HBY0.1 |
UniProt Secondary Accession: | Q9HBY0,Q9HBJ9, |
UniProt Related Accession: | Q9HBY0 |
Molecular Weight: | 64,935 Da |
NCBI Full Name: | NADPH oxidase 3 |
NCBI Synonym Full Names: | NADPH oxidase 3 |
NCBI Official Symbol: | NOX3 |
NCBI Official Synonym Symbols: | MOX-2; GP91-3 |
NCBI Protein Information: | NADPH oxidase 3 |
UniProt Protein Name: | NADPH oxidase 3 |
UniProt Synonym Protein Names: | Mitogenic oxidase 2; MOX-2; gp91phox homolog 3; GP91-3 |
Protein Family: | NADPH oxidase |
UniProt Gene Name: | NOX3 |
UniProt Entry Name: | NOX3_HUMAN |