NOB1 Antibody (PACO51206)
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주문- SKU:
- PACO51206
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NOB1 Antibody (PACO51206) |
Antibody SKU: | PACO51206 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human RNA-binding protein NOB1 protein (103-229AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, Mouse brain tissue, Mouse kidney tissue, Mouse stomach tissue. All lanes: NOB1 antibody at 1.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO51206 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO51206 at dilution of 1:100. |
Background: | May play a role in mRNA degradation. |
Synonyms: | RNA-binding protein NOB1 (Phosphorylation regulatory protein HP-10) (Protein ART-4), NOB1, ART4 NOB1P PSMD8BP1 |
UniProt Protein Function: | NOB1P: May play a role in mRNA degradation. Belongs to the NOB1 family. |
UniProt Protein Details: | Protein type:RNA processing Chromosomal Location of Human Ortholog: 16q22.3 Cellular Component: cytosol; nucleolar preribosome, small subunit precursor; nucleoplasm Molecular Function:endoribonuclease activity Biological Process: cleavages during rRNA processing; maturation of SSU-rRNA; rRNA processing |
NCBI Summary: | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q9ULX3 |
NCBI GenInfo Identifier: | 74753398 |
NCBI Gene ID: | 28987 |
NCBI Accession: | Q9ULX3.1 |
UniProt Secondary Accession: | Q9ULX3,Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0, |
UniProt Related Accession: | Q9ULX3 |
Molecular Weight: | 46,675 Da |
NCBI Full Name: | RNA-binding protein NOB1 |
NCBI Synonym Full Names: | NIN1/PSMD8 binding protein 1 homolog |
NCBI Official Symbol: | NOB1 |
NCBI Official Synonym Symbols: | ART-4; NOB1P; MST158; MSTP158; PSMD8BP1 |
NCBI Protein Information: | RNA-binding protein NOB1 |
UniProt Protein Name: | RNA-binding protein NOB1 |
UniProt Synonym Protein Names: | Phosphorylation regulatory protein HP-10; Protein ART-4 |
Protein Family: | Endoribonuclease |
UniProt Gene Name: | NOB1 |
UniProt Entry Name: | NOB1_HUMAN |